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This phrase is a quality-assurance claim stating that every manufactured batch of the peptide has been lab-tested and verified to contain at least 99% of the intended molecule, using industry gold-standard testing methods.
A "lot" (or batch) is a specific production run. "All lots" means every single batch manufactured undergoes testing, not just an occasional sample.
At least 99% of the peptide material present is the exact, full-length target peptide. The remaining <1% consists of minor synthesis byproducts (like truncated peptide chains or deletion sequences).
A separation technique that pumps the liquid sample through a column under high pressure. It physically separates the target peptide from impurities and measures purity percentage based on UV absorption peaks.
A detection method paired with HPLC that measures the exact mass-to-charge ratio (m/z) of the molecules. It confirms the chemical identity and exact molecular weight to ensure the peptide synthesized is actually the intended compound, not a lookalike.
Peptide synthesis is built step-by-step, amino acid by amino acid. Errors during synthesis can create incomplete chains or modified sequences. Pairing HPLC with Mass Spectrometry ensures two critical things: HPLC confirms how pure it is, and MS confirms what it is.